Prediabetes Is the Quiet Driver of ED
15 minJune 2026
Steven opens his office hours under the erection most clinics chase and finds the metabolism nobody screens: prediabetes....
Evidence behind this episode
- Alshahrani 2025
Meta-analysis, men with prediabetes carry roughly 2.5x the odds of sexual dysfunction vs normoglycemic men (pooled OR, 95% CI ~1.35-4.64). Direction only, never a hard multiplier as settled: certainty is LOW with I2=87.9% heterogeneity (a sibling 2022 meta-analysis, PMID 35082752, gives ~1.62x), so stay on "substantially higher risk" and frame 2.5x as the low-certainty headline estimate.